Part I Sepsis
1 Effect of Sex and Gender in Sepsis and Septic Shock:
A Narrative Review 3
A. Lopez, I. Lakbar, and M. Leone
2 Complex Immune Dysregulation in COVID-19 and
Implications for Treatment 15
M. Mouktaroudi and E. J. Giamarellos-Bourboulis
3 Measuring Vitamin C in Critically Ill Patients: Clinical Importance
and Practical Difficulties—Is It Time for a Surrogate Marker? 25
S. Rozemeijer, F. A. L. van der Horst, and A. M. E. de Man
4 Controversies on Non-renal Extracorporeal Therapies in
Critically Ill COVID-19 Patients 35
S. Romagnoli, Z. Ricci, and C. Ronco
5 Secondary Infections in Critically Ill Patients with COVID-19 43
G. Grasselli, E. Cattaneo, and G. Florio
Part II Shock
6 Heart Dysfunction in Septic Patients: From Physiology to
Echocardiographic Patterns 55
A. Messina, F. Villa, and M. Cecconi
7 Non-adrenergic Vasopressors in Septic Shock: Overview
and Update 67
E. Antonucci, M. Giovini, and Y. Sakr
8 Pathophysiology and Clinical Implications of the Veno-arterial
PCO2 Gap 79
Z. Ltaief, A. G. Schneider, and L. Liaudet
9 Still a Place for Aortic Counterpulsation in Cardiac Surgery
and Patients with Cardiogenic Shock? 93
M. Heringlake, A. E. Berggreen, and H. Paarmann
Part III The Microcirculation
10 The Clinical Relevance of High-Altitude Microcirculation
Studies: The Example of COVID-19 103
G. Capaldo, C. Ince, and M. P. Hilty
11 Observation of Leukocyte Kinetics Using Handheld Vital
Microscopes During Surgery and Critical Illness 111
Z. Uz, C. Ince, and M. S. Arbous
Part IV Airway and Non-invasive Ventilation
12 Tracheostomy for COVID-19: Evolving Best Practice 125
T. Williams and B. A. McGrath
13 Modernizing Tracheostomy Practice to Improve Resource
Utilization and Survivorship Outcomes 139
G. Hernandez, M. Brenner, and B. A. McGrath
14 Helmet Non-invasive Ventilation in Acute Hypoxemic
Respiratory Failure Due to COVID-19 153
S. Aldekhyl, H. Tlayjeh, and Y. Arabi
Part V Acute Respiratory Distress Syndrome
15 Mechanisms of Hypoxemia in the Acute Respiratory Distress
Syndrome 167
I. Marongiu, B. Pavlovsky, and T. Mauri
16 To Prone or Not to Prone ARDS Patients on ECMO 177
O. Roca, A. Pacheco, and M. García-de-Acilu
17 Mesenchymal Stromal Cell Therapy in Typical ARDS and
Severe COVID-19 191
F. F. Cruz, P. R. M. Rocco, and P. Pelosi
Part VI Renal Issues
18 Acute Kidney Injury in ECMO Patients 207
M. Ostermann and N. Lumlertgul
19 Management of Acute Metabolic Acidosis in the ICU: Sodium
Bicarbonate and Renal Replacement Therapy 223
K. Yagi and T. Fujii
20 Critically Ill Patients with Acute Kidney Injury: Focus on
Nutrition 233
L. Foti, G. Villa, and S. Romagnoli
Part VII Acute Brain Injury
21 Carbon Dioxide Management in TBI: From Theory
to Practice 245
E. Rossi, L. Malgeri, and G. Citerio
22 Monitoring and Modifying Brain Oxygenation in Patients at
Risk of Hypoxic Ischemic Brain Injury After Cardiac Arrest 253
M. B. Skrifvars, M. Sekhon, and A. Åneman
23 ICU Delirium in the Era of the COVID-19 Pandemic 267
K. Kotfis, J. E. Wilson, and E. W. Ely
Part VIII Emergencies
24 Advanced Management of Intermediate-High
Risk
Pulmonary Embolism 283
T. Weinstein, H. Deshwal, and S. B. Brosnahan
25 Enhancing Non-ICU Clinician Capability and ICU Bed
Capacity to Manage Pandemic Patient Surge 295
H. Bailey and L. J. Kaplan
Index 305
Annual Update in Intensive Care and Emergency Medicine 2021 PDF Ebook
