BRS Pharmacology 7th Edition PDF

Acknowledgments vi
1. FUNDAMENTAL PRINCIPLES OF PHARMACOLOGY
I. Dose-Response Relationships 1
II. Pharmacokinetics and Pharmacodynamics 6
Ill. Drug Absorption 7
IV. Drug Distribution 10
V. Metabolism (Biotransformation) of Drugs 11
VI. Drug Elimination and Termination of Action 13
VII. Pharmacokinetic Principles 15
RaviawTall 19
2. DRUGS ACTING ON THE AUTONOMIC
NERVOUS SYSTEM
I. ‘Ihe Nervous System 24
II. ‘Ihe Peripheral Efferent Nervous System 24
Ill. Parasympathomimetic Drugs 30
IV. Anticbolinergic Drugs 34
V. Sympathomimetic Drugs 40
VI. Adrenergic Receptor Antagonists 44
R1viawT111 48
3. DRUGS ACTING ON THE RENAL SYSTEM
I. Diuretics 55
II. Antidiuretic Drugs 60
R1vi1wT111 63
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24
55
4. DRUGS ACTING ON THE CARDIOVASCULAR SYSTEM 67
I. Antihypertensive Drugs 67
II. Agents Used to Treat Congestive Heart Failure 73
Ill. Antianginal Agents 76
IV. Anti.anhythmic Drugs 77
V. Drugs that Lower Plasma lipids 83
Review Tell 87
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5.
6.
7.
8.
DRUGS ACTING ON THE CENTRAL NERVOUS SYSTEM
I. Sedative-Hypnotic Drugs 92
II. Antipsychotic (Neuroleptic) Drugs 96
Ill. Antidepressant Drugs 100
IV. lithium (and Anticonvulsants Used to Treat Bipolar Disorder) 105
V. Drugs Used to Treat Parkinson Disease 106
VI. Drugs Used to Treat Alzheimer Disease 109
VII. Antiepileptic Drugs llO
VIII. General Anesthetics ll3
IX. Local Anesthetics 117
X. Opioid Analgesics and Antagonists 119
XI. Drugs of Abuse 123
Review Test 133
AUTOCOIDS, ERGOTS, ANTI-INFLAMMATORY AGENTS,
AND IMMUNOSUPPRESSIVE AGENTS
I. Histamine and Antihistamines 138
II. Serotonin Agonists and Antagonists 140
Ill. Ergot Alkaloids 141
IV. Eicosanoids 142
V. Salicylates and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) 144
VI. Drugs Used for Gout 147
VII. Immunosuppressive Drugs 148
Raviaw Tast 154
DRUGS USED IN ANEMIA AND DISORDERS
OF HEMOSTASIS
I. Drugs Used in the Treatment of Anemia 158
II. Drugs Acting on Myeloid Cells 162
Ill. Drugs Used in Hemostatic Disorders 162
Raviaw Tast 172
DRUGS ACTING ON THE GASTROINTESTINAL TRACT
I. Antiemetics 177
II. Drugs Used to Manage Obesity 179
Ill. Drugs Used to Increase Appetite 180
IV. Agents Used for Upper GI Tract Disorders 180
V. Drugs Used to Dissolve Gallstones 183
VI. Digestive Enzyme Replacements 183
VII. Agents that Act on the Lower GI Tract 183
ReviewTest 189
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138
158
177
Contents ix
9. DRUGS ACTING ON THE PULMONARY SYSTEM
I. Introduction to Pulmonary Disorders 193
II. Agents Used to Treat Asthma and Other Bronchial Disorders 194
Ill. Drugs Used to Treat Rhinitis and Cough 199
Review Test 202
10. DRUGS ACTING ON THE ENDOCRINE SYSTEM
I. Hormone Receptors 205
II. Tue Hypothalamus 205
Ill. Tue Anterior Pituitary 209
IV. Tue Posterior Pituitary 211
V. Drugs Acting on the Gonadal and Reproductive System 213
VI. Tue Adrenal Cortex 219
VII. Tue Thyroid 223
VIII. Tue Pancreas and Glucose Homeostasis 226
IX. Tue Calcium Homeostatic System 232
X. Retinoic Acid and Derivatives 235
Review Test 238
193
205
11. DRUGS USED IN TREATMENT OF INFECTIOUS DISEASES 241
I. Infectious Disease Therapy 241
II. Antibacterial Agents: Inhibitors of Bacterial Cell Wall Biosynthesis 242
Ill. Antibacterial Agents: Inhibitors ofBacterial Protein Synthesis 248
IV. Antibacterial Agents: Inhibitors of DNA Synthesis and Integrity 252
V. Antibacterial Agents: Miscellaneous Drugs 254
VI. Antimycobacterial Agents 254
VII. Antifungal Agents 256
VIII. Antiparasitic Drugs 258
IX. Antiviral Drugs 262
X. Antiretroviral Drugs 264
Review Test 269
12. CANCER CHEMOTHERAPY
I. Principles of Cancer Chemotherapy 27 4
II. Alkylating Agents 277
Ill. Antimetabolites 279
IV. Microtubule Damaging Agents 281
V. Topoisomerase Inhibitors 282
VI. Antitumor Antibiotics 283
VII. Miscellaneous Antineoplastic Agents 284
VIII. Targeted Therapy 284
IX. Corticosteroids 287
X. Hormone Therapy 287
Review Test 291
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13. TOXICOLOGY
I. Principles and Terminology 296
II. Air Pollutants 298
Ill. Solvents 300
IV. Insecticides and Herbicides 301
V. Heavy Metal Poisoning and Management 302
VI. Drug Poisoning 305
Review Test 307
Camp18hensiv11 Examination
BRS Pharmacology 7th Edition PDF Ebook

Sarah Lerchenfeldt, PharmD
Asatatant Professor
Department of Foundational Medical Studies
Oakland University William Beaumont School of Medicine
Rochestelf Miclllgan