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Fitzpatrick’s Dermatology in General Medicine 8th Edition PDF Free Download
The landmark dermatology text that bridges the gap between science and clinical medicine-updated for today’s practice
Generations of clinicians, skin biologists, residents, and educators have acclaimed Fitzpatrick’s as the most authoritative and complete guide to dermatologic basic sciences, histopathology, diagnosis, and treatment. Edition after edition, it reflects the latest insights into skin diseases and skin biology-and their practical relevance to general internal medicine-while covering the scientific foundations of the specialty.
This classic yet cutting-edge text is supported by the expert insights of more than 500 internationally respected contributors, and it covers everything dermatologists need to know about skin, dermatologic signs of underlying disease, and the management of all skin diseases, including acne, skin cancer, and psoriasis.
KEY FEATURES :
More than 3000 full-color photographs
DVD with image bank includes downloadable figures from the text
New illustration style makes difficult concepts easier to understand
Therapeutic ladders with first, second, and third line therapies
New or thoroughly revised chapters on Psoriasis;Skin disease in immunosuppressed patients; Epidermal stem cells; Hair growth disorders; Neonatal, pediatric, and adolescent
dermatology; Radiotherapy; Immunobiologicals and cytokines; Lasers for rejuvenation
Expanded medical and surgical therapeutics sections guide you through all treatment options
E-Book Details
Сategories: Medicine|Dermatology
No. of pages: 3190
Language: English
File Size : 283 MB
File Format : PDF
No. of pages: 3190
Language: English
File Size : 283 MB
File Format : PDF
Table of Contents
Contributors
Preface
Acknowledgments
PART I: INTRODUCTION
Section 1: General Considerations
1. The Epidemiology and Burden of Skin Disease, Martin A. Weinstock and Mary-Margaret Chren
2. Evidence-Based Dermatology, Michael Bigby, Rosamaria Corona, and Moyses Szklo
3. Global Health in Dermatology, Roderick Hay
4. Public Health in Dermatology, Hywell C. Williams, Sinead Langan, and Carsten Flohr
Section 2: Approach to Dermatologic Diagnosis
5. Structure of Skin Lesions and Fundamentals of Clinical Diagnosis, Amit Garg, Nikki A. Levin, and Jeffrey D. Bernhard
6. Basic Pathologic Reactions of the Skin, Klaus Wolff
Section 3: Overview of Biology, Development, and Structure of Skin
7. Development and Structure of Skin, David H. Chu
8. Genetics in Relation to the Skin, John McGrath and Irwin McLean
9. Racial Considerations: Skin of Color, Kavitha K. Reddy, Yolanda M. Lenzy, Katherine L. Brown, and Barbara A. Gilchrest
PART II: DISORDERS PRESENTING IN SKIN AND MUCOUS MEMBRANES
Section 4: Inflammatory Disorders Based on T-Cell Reactivity and Dysregulation
10. Innate and Adaptive Immunity for the Skin, Georg Stingl and Robert L. Modlin
11. Cytokines, Thomas Kupper and Ifor Williams
12. Chemokines, Anke S. Lonsdorf and Sam T. Hwang
13. Allergic Contact Dermatitis, Kathryn A. Zug and Mari Paz Castanedo
14. Atopic Dermatitis (Atopic Eczema), Donald Leung, Lawrence F. Eichenfield, and Mark Boguniewicz
15. Nummular Eczema and Lichen Simplex Chronicus/Prurigo Nodularis, Susan Burgin
16. Vesicular Palmoplantar Eczema, Daven N. Doshi, Carol E. Cheng, and Alexa B. Kimball
17. Autosensitization Dermatitis, Don Belsito
18. Psoriasis, James T. Elder
19. Psoriatic Arthritis, Dafna D. Gladman and Vinod Chandran
20. Reactive Arthritis, John D. Carter
21. Pustular Eruptions of Palms and Soles, Ulrich Mrowietz
22. Seborrheic Dermatitis, Chad M. Hivnor and Chris D. Collins
23. Exfoliative Dermatitis, Jane Margaret Grant-Kels, Flavia Fedeles, and Marti J. Rothe
24. Pityriasis Rubra Pilaris, Daniela Bruch-Gerharz and Thomas Ruzicka
25. Parapsoriasis and Pityriasis Lichenoides, Gary S. Wood, Chung-Hong Hu, and Rosemarie Liu
26. Lichen Planus, Mark R. Pittelkow and Mazen Daoud
27. Lichen Nitidus, Mark R. Pittelkow and Mazen Daoud
28. Graft-versus-Host Disease, Ed Cowen
29. Skin Disease in Acute and Chronic Immunosuppression, Benjamin D. Ehst and Andrew Blauvelt
Section 5: Inflammatory Diseases Based on Neutrophilsand Eosinophils
30. Regulation of the Production and Activation of Neutrophils, Steven M. Holland
31. Regulation of the Production and Activation of Eosinophils, Kristin M. Leiferman
32. Acute Febrile Neutrophilic Dermatosis (Sweet Syndrome), Philip R. Cohen, Herbert Hoenigsmann, and Razelle Kurzrock
33. Pyoderma Gangrenosum, Frank C. Powell, Bridget C. Hackett, and Daniel Wallach
34. Granuloma Faciale, David A. Mehregan and Darius R. Mehregan
35. Sub-Corneal Pustular Dermatosis (Sneddon-Wilkinson Disease), Franz Trautinger and Herbert Hoenigsmann
36. Eosinophils in Cutaneous Diseases, Kristin M. Leiferman and Margot S. Peters
Section 6: Inflammatory Diseases Based on Abnormal Humoral Reactivity and Other Inflammatory Diseases
37. Humoral Immunity and Complement, Lela Lee
38. Urticaria and Angioedema, Allen Kaplan
39. Erythema Multiforme, Jean C. Roujeau
40. Epidermal Necrolysis (Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis), L. Valeyrie-Allanore and Jean C. Roujeau
41. Cutaneous Reactions to Drugs, Neil H. Shear and Sandra R. Knowles
42. Pityriasis Rosea, Andrew Blauvelt
43. Erythema Annulare Centrifugum and Other Figurate Erythemas, Walter H. C. Burgdorf
44. Granuloma Annulare, Julie S. Prendiville
Section 7: Disorders of Epidermal Differentiation and Keratinization
45. Epidermal Stem Cells, Rebecca Morris
46. Epidermal Growth and Differentiation, Tung-Tien Sun
47. Skin as an Organ of Protection, Ehrhardt Proksch and Jens-Michael Jensen
48. Irritant Contact Dermatitis, Antoine Amado, Apra Sood, and James S. Taylor
49. The Ichthyoses, Philip Fleckman and John DiGiovanna
50. Inherited Keratodermas of Palms and Soles, Mozheh Zamiri, Maurice A.M. van Steensel, and Colin S. Munro
51. Acantholytic Disorders of the Skin, Susan Burge and Alain Hovnanian
52. Porokeratosis, Alan D. Irvine and Grainne O’Regan
Section 8: Disorders of Epidermal and Dermal-Epidermal Cohesion and Vesicular and Bullous Disorders
53. Epidermal and Epidermal-Dermal Abrasion, Leena Bruckner-Tuderman and Aimee S. Payne
54. Pemphigus, John R. Stanley and Aimee S. Payne
55. Paraneoplastic Pemphigus, Grant Anhalt and Daniel Mimouni
56. Bullous Pemphigoid, Donna A. Culton, Zhi Liu, and Luis A. Diaz
57. Cicatricial Pemphigoid, Kim B. Yancey
58. Linear Immunoglobulin A Dermatosis and Chronic Bullous Disease of Childhood, Caroline L. Rao and Russell P. Hall, III
59. Pemphigoid Gestationis (Herpes Gestationis), Jeff Shornick
60. Epidermolysis Bullosa Acquisita, David T. Woodley and Mei Chen
61. Dermatitis Herpetiformis, Arash Ronaghy, Stephen I. Katz, and Russell P. Hall, III
62. Inherited Epidermolysis Bullosa, M. Peter Marinkovich
Section 9: Disorders of the Dermal Connective Tissue
63. Collagens, Elastic Fibers, and Other Extracellular Matrix Proteins of the Dermis, Thomas Krieg, Monique Aumailley, Manual Koch, Mon-Li Chu, and Jouni Uitto
64. Morphea, Stephanie Saxton-Daniels and Heidi Jacobe
65. Lichen Sclerosus, Ulrich Hengge
66. Dermal Hypertrophies and Benign Fibroblastic/Myofibroblastic Tumors, Christine Ko
67. Anetoderma and Other Atrophic Disorders of the Skin, Julie Powell and Catherine Maari
68. Ainhum and Pseudoainhum, Robert T. Brodell and Stephen E. Helms
69. Acquired Perforating Disorders, Bethanee Schlosser and Julia Minocha
Section 10: Disorders of Subcutaneous Tissue
70. Panniculitis, Iris K. Aronson, Patricia M. Fishman, and Sophie M. Worobec
71. Lipodystrophy, Abhimanyu Garg
Section 11: Disorders of Melanocytes
72. Biology of Melanocytes, Hee-Young Park, Marita G. Kosmadaki, Marinya Pongpudpunth, Jin Lee, and Mina Yaar
73. Albinism and Other Genetic Disorders of Pigmentation, Thomas J. Hornyak
74. Vitiligo, Stanca A. Birlea, Richard A. Spritz, and David A. Norris
75. Hypomelanoses and Hypermelanoses, Hilde Lapeere, Barbara Boone, Sofie De Schepper, Evelien Verhaeghe, Mireille Van Gele, Katia Ongenae, Nanja Van Geel, Jo Lambert, Lieve Brochez, and Jean-Marie Naeyaert
Section 12: Disorders of the Oral and Genital Integument
76. Biology and Pathology of the Oral Cavity, Sook-Bin Woo
77. Diseases and Disorders of the Male Genitalia, Christopher Barry Bunker
78. Diseases and Disorders of the Female Genitalia, Lynne Margesson and F. William Danby
PART III: DISORDERS OF THE SKIN APPENDAGES
Section 13: Disorders of the Sebaceous Glands
79. Biology of Sebaceous Glands, Amanda M. Nelson and Diane M. Thiboutot
80. Acne Vulgaris and Acneiform Eruptions, Andrea L. Zaenglein, Emmy M. Graber, Diane M. Thiboutot, and John S. Strauss
81. Rosacea, Michelle Terez Pelle
82. Perioral Dermatitis, Leslie P. Lawley and Sareeta R.S. Parker
Section 14: Disorders of the Eccrine and Apocrine Glands
83. Biology of Eccrine, Apocrine, and Apoeccrine Sweat Glands, Theodora Marie Mauro
84. Disorders of the Eccrine Sweat Glands and Sweating, Robert D. Fealey and Adelaide A. Herbert
85. Disorders of the Apocrine Sweat Glands, Christos C. Zouboulis and Fragkiski Tsatsou
Section 15: Disorders of the Hair and Nails
86. Biology of Hair Follicles, George Cotsarelis and Vladimir Botchkarev
87. Keratosis Pilaris and Other Inflammatory Follicular Keratotic Syndromes, Paradi Mirmirani and Maureen Rogers
88. Hair Growth Disorders, Nina Otberg and Jerry Shapiro
89. Biology of Nails and Nail Disorders, Antonella Tosti and Bianca Maria Piraccini
PART IV: DISORDERS DUE TO THE ENVIRONMENT
Section 16: Disorders Due to Ultraviolet Radiation
90. Fundamentals of Cutaneous Photobiology and Photoimmunology, Irene Kochevar, Charles Taylor, and Jean Krutmann
91. Abnormal Responses to Ultraviolet Radiation: Idiopathic, Probably Immunologic, and Photoexacerbated, Paul Bergstresser
92. Abnormal Responses to Ultraviolet Radiation: Photosensitivity Induced by Exogenous Agents, Henry W. Lim
Section 17: Skin Changes Due to Other Physical and Chemical Factors
93. Thermoregulation, Dean L. Kellogg, Jr.
94. Cold Injuries, Gerald E. Pieard, Pascale Quatresooz, and Claudine Pierard-Franchimont
95. Thermal Injuries, Robert L. Sheridan
96. Skin Problems in Amputees, Calum Lyon and Michael H. Beck
97. Skin Problems in Ostomates, Calum Lyon and Michael Beck
98. Corns and Calluses, Thomas M. DeLauro and Nicole M. DeLauro
99. Sports Dermatology, Dirk M. Elston
100. Decubitus (Pressure) Ulcers, Jennifer Gloeckner Powers, Lilian M. Odo, and Tania J. Phillips
101. Body Art, Anne Laumann
PART V: NEUROCUTANEOUS AND
PSYCHOCUTANEOUS ASPECTS OF SKIN DISEASE
Section 18: Neurocutaneous and Psychocutaneous Skin Disease
102. Neurobiology of the Skin, Thomas Luger and Martin Steinhoff
103. Pathophysiology and Clinical Aspects of Pruritus, Gil Yosipovitch and Tejesh S. Patel
104. Psychocutaneous Skin Disease, Evan Rieder and Francisco A. Tausk
105. Cutaneous Manifestations of Drug Abuse, Richard A. Johnson and Haley Naik
106. Skin Signs of Physical Abuse, Howard Pride
PART VI: SKIN CHANGES ACROSS THE LIFE SPAN
Section 19: From Birth to Old Age
107. Neonatal, Pediatric, and Adolescent Dermatology, Mary W. Chang
108. Skin Changes and Diseases in Pregnancy, Julie K. Karen and Miriam Keltz Pomeranz
109. Aging of Skin, Barbara Ann Gilchrest and Mina Yaar
PART VII: NEOPLASIA
Section 20: Carcinogenesis
110. Genome Instability, DNA Repair, and Cancer, Kenneth H. Kraemer and Thomas M. Ruenger
111. Chemical Carcinogenesis, Andrzej A. Dlugosz
112. Ultraviolet Radiation Carcinogenesis, Masaoki Kawasumi and Paul Nghiem
Section 21: Epidermal and Appendageal Tumors
113. Epithelial Precancerous Lesions, Karyanne O. Duncan, John K. Geisse, and David J. Leffell
114. Squamous Cell Carcinoma, David J. Leffell and Douglas Grossman
115. Basal Cell Carcinoma, David J. Leffell and John Carucci
116. Basal Cell Nevus Syndrome, Anthony E. Oro and Jean Y. Tang
117. Keratoacanthoma, Lorenzo Cerroni and Helmut Kerl
118. Benign Epithelial Tumors, Hamartomas, and Hyperplasias, Neil Swanson
119. Appendage Tumors and Hamartomas of the Skin, Divya Srivastava and R. Stan Taylor
120. Merkel Cell Carcinoma, Andrew Tegeder, Olga Afanasiev, and Paul Nghiem
121. Mammary and Extramammary Paget Disease, Sherrif F. Ibrahim, Roy C. Greken, and Isaac M. Neuhaus
Section 22: Melanocytic Tumors
122. Benign Neoplasias and Hyperplasias of Melanocytes, James M. Grichnik, Arthur R. Rhodes, and Arthur J. Sober
123. Atypical (Dysplastic) Melanocytic Nevi, James Grichnik and Margaret A. Tucker
124. Cutaneous Melanoma, Evans C. Bailey, Arthur J. Sober, Hensin Tsao, Martin C. Mihm, Jr., and Timothy M. Johnson
Section 23: Tumors and Hyperplasias of the Dermis and Subcutaneous Fat
125. Malignant Fibrous, Fibrohistiocytic, and Histiocytic Tumors of the Dermis, Juergen C. Becker and Selma Ugurel
126. Vascular Tumors, Ilona J. Frieden and Erin Mathes
127. Neoplasias and Hyperplasias of Muscular and Neural Origin, Lucile E. White, Ross M. Levy, and Murad Alam
128. Kaposi Sarcoma, Erwin Tschachler
129. Neoplasms of Subcutaneous Fat, Thomas Brenn
PART VIII: THE SKIN IN SYSTEMIC DISEASE
Section 24: Skin in Nutritional, Metabolic, and Heritable Disease
130. Cutaneous Features of Nutritional Disease, Albert C. Yan and Melinda Jen
131. Cutaneous Changes in Errors of Amino Acid Metabolism, Peter Itin
132. The Porphyrias, David R. Bickers and Jorge Frank
133. Amyloidosis and the Skin, Helen J. Lachmann and Philip Hawkins
134. The Systemic Monogenic Autoinflammatory Diseases, Raphaela Goldbach-Mansky
135. Xanthomatoses and Lipoprotein Disorders, Ernst Schaefer and Raul Santos
136. Fabry Disease, Atul Mehta and Catherine H. Orteu
137. Lipoid Proteinosis and Heritable Disorders of Connective Tissue, Jon Dyer
138. Cutaneous Mineralization and Ossification, Janet Fairley
139. Hereditary Disorders of Genome Instability and DNA Repair, Thomas Ruenger, Kenneth H. Kraemer, and John DiGiovanna
140. Tuberous Sclerosis Complex, Thomas N. Darling
141. The Neurofibromatoses, Robert H. Listernick and Joel Charrow
142. Ectodermal Dysplasias, Nnenna Agim, Alanna F. Bree, and Virginia P. Sybert
143. Genetic Immunodeficiency Diseases, Ramsey Fuleihan and Amy Paller
Section 25: Skin Manifestations of Bone Marrow or Blood Chemistry Disorders
144. Hematologic Diseases, Warren Piette
145. Cutaneous Lymphoma, Marc Beyer and Wolfgang Sterry
146. Inflammatory Diseases That Simulate Lymphomas: Cutaneous Pseudolymphomas, Gary S. Wood
147. Cutaneous Langerhans Cell Histiocytosis, Carlo Gelmetti
148. Non-Langerhans Cell Histiocytosis, Carlo Gelmetti
149. Mastocytosis, Michael D. Thorp
Section 26: Skin Manifestations of Internal Organ Disorders
150. The Skin and Disorders of the Alimentary Trace, the Hepatobiliary System, Kidney and Cardiopulmonary System, Graham A. Johnston and Robin A.C. Graham-Brown
151. Diabetes Mellitus and Other Endocrine Diseases, Andrea A. Kalus, Andy J. Chien, and John E. Olerud
152. Sarcoidosis, Richard M. Marchell, Bruce Thiers, and Marc Judson
153. Cutaneous Manifestations of Internal Malignant Disease, Christine DeWitt, Lucinda Buescher, and Stephen P. Stone
Section 27: The Skin in Vascular and Connective Tissue and Other Autoimmune Disorders
154. Mechanisms of Autoimmune Disease, Joseph Craft and Insoo Kang
155. Lupus Erythematosus, Richard D. Sontheimer and Melissa I. Costner
156. Dermatomyositis, Richard D. Sontheimer and Melissa I. Costner
157. Scleroderma (Systematic Sclerosis), P. Moinzadeh, C.P. Denton, T. Kriegm and C.M. Black
158. Scleredema and Scleromyxedema, Roger H. Weenig and Mark R. Pittelkow
159. Relapsing Polychondritis, Camille Frances
160. Rheumatoid Arthritis, Rheumatic Fever, and Gout, Warren Piette
161. Sjoegren Syndrome, Gabor Illei
Section 28: The Skin in Inflammatory and Other Vascular Disorders
162. Endothelium in Inflammation and Angiogenesis, Peter Petzelbauer, Robert Loewe, and Jordan S. Pober
163. Cutaneous Necrotizing Venulitis, Nicholas A. Soter
164. Systemic Necrotizing Arteritis, Peter Merkel
165. Erythema Elevatum Diutinum, Nneka J. Comfere and Lawrence E. Gibson
166. Adamantiades-Behcet Disease, Christos C. Zouboulis
167. Kawasaki Disease, Anne H. Rowley
168. Pigmented Purpuric Dermatoses, Theresa Devere
169. Cryoglobulinemia and Cryofibrinogenemia, Holger Schmidt and Gerald Braun
170. Raynaud Phenomenon, John H. Klippel
171. Malignant Atrophic Papulosis (Degos Disease), Dan Lipsker
172. Vascular Malformations, Laurence M. Boon
173. Cutaneous Changes in Peripheral Vascular Arterial Disease, Veerendra Chadachan, Steven M. Dean, and Robert T. Eberhardt
174. Cutaneous Changes in Venous and Lymphatic Insufficiency, Craig N. Burkhart, Chris Adigun, and Claude S. Burton
PART IX: DISEASE DUE TO MICROBIAL AGENTS, INFESTATIONS, BITES, AND STINGS
Section 29: Bacterial Disease
175. General Considerations of Bacterial Diseases, Noah Craft
176. Superficial Cutaneous Infections and Pyodermas, Noah Craft
177. Gram-Positive Infections Associated with Toxin Production, Jeffrey B. Travers and Nick Mousdicas
178. Non-Necrotizing Infections of the Dermis and Subcutaneous Fat: Cellulitis and Erysipelas, Adam D. Lipworth, Arturo Saavedra, Arnold N. Weinberg, and Richard Allen Johnson
179. Necrotizing Soft Tissue Infections: Necrotizing Fasciitis, Gangrenous Cellulitis, and Myonecrosis, Adam P. Lipworth, Arturo Saavedra, Arnold N. Weinberg, and Richard Allen Johnson
180. Gram-Negative Coccal and Bacillary Infections, Myron Cohen and David Weber
181. The Skin in Infective Endocarditis, Sepsis, Septic Shock, and Disseminated Intravascular Coagulation, Laura Korb Ferris and Joseph C. English
182. Bartonellosis, Timothy Berger and Francisco G. Bravo
183. Miscellaneous Bacterial Infections with Cutaneous Manifestations, Scott A. Norton
184. Tuberculosis and Infections with Atypical Mycobacteria, Aisha Sethi and Bernard Naafs
185. Actinomyosis, Nocardiosis, and Actinomycetoma, Francisco G. Bravo, Roberto Arenas, and Daniel Asz Sigall
186. Leprosy, Delphine Lee, Thomas H. Rea, and Robert L. Modlin
187. Lyme Borreliosis, Meera Mahalingam, Jag Bhawan, Daniel B. Eisen, and Linden Hu
Section 30: Fungal Diseases
188. Superficial Fungal Infection, Amit Garg and Stefan Schieke
189. Yeast Infections: Candidiasis, Tinea (Pityriasis) Versicolor and Malassezia (Pityrosporum) Folliculitis, Roopal Vashi Kundu and Amit Garg
190. Deep Fungal Infections, Roderick J. Hay
Section 31: Viral and Rickettsial Diseases
191. Viral Diseases: General Considerations, L. Katie Morrison, Ammar Ahmed, Vandana Madkan, Natalia Mendoza, and Stephen Tyring
192. Exanthematous Viral Diseases, Leah T. Belazarian, Mayra E. Lorenzo, Andrea L. Pearson, Susan M. Sweeney, and Karen Wiss
193. Herpes Simplex, Adriana R. Marques and Jeffrey I. Cohen
194. Varicella and Herpes Zoster, Kenneth Schmader and Michael N. Oxman
195. Poxvirus Infections, Caroline Piggott, Sheila Fallon Friedlander, and Wynnis Tom
196. Warts, Elliott J. Androphy and Reinhard Kirnbauer
197. Human Retroviral Disease: Human T-Lymphotropic Viruses, Erwin Tschachler
198. Cutaneous Manifestations of Human Immunodeficiency Virus, Lily Changchien Uihlein, Arturo Saavedra, and Richard Allen Johnson
199. The Rickettsioses, Ehrlichioses, and Anaplasmoses, Warren Heyman, Sandra Kopp, and Justin Green
Section 32: Sexually Transmitted Diseases
200. Syphilis, Ken Katz
201. Endemic (Non-venereal) Treponematoses, Samer
Ghosn and Nadine Marrouch
202. Chancroid, Stephan Lautenschlager
203. Lymphogranuloma Venereum, Rim Ishak and Samer Ghosn
204. Granuloma Inguinale, Abdul-Ghani Kibbi, Ruba F. Bahhady, and Myrna El-Shareef
205. Gonorrhea and Other Mucosal-Based Venereal Diseases, Ted Rosen
Section 33: Infestations, Bites, and Stings
206. Leishmaniasis and Other Protozoan Infections, Joelle Malek and Samar Ghosn
207. Helminthic Infections, Jay Keystone and Kathy Suh
208. Scabies, Other Mites, and Pediculosis, Craig N. Burkhart and Craig G. Burkhart
209. Bites and Stings of Terrestrial and Aquatic Life, Jennifer Daly and Mark Jordan Scharf
210. Arthropod Bites and Stings, Robert A. Schwartz and Christopher J. Steen
PART X: OCCUPATIONAL SKIN DISEASES AND SKIN DISEASES DUE TO BIOLOGIC WARFARE
Section 34: Occupational Skin Diseases
211. Occupational Skin Disease due to Irritants and Allergens, James S. Taylor and Apra Sood
212. Occupational Noneczematous Skin Diseases Due to Biologic, Physical, and Chemical Agents: Introduction, James S. Taylor and Apra Sood
Section 35: The Skin in Bioterrorism and Biologic Warfare
213. Cutaneous Manifestations of Biologic, Chemical, and Radiologic Terrorism Attacks, Scott A. Norton
PART XI: THERAPEUTICS
Section 36: Topical Therapy
214. Principles of Topical Therapy, Aieska de Souza and Bruce E. Strober
215. Pharmacokinetics and Topical Applications of Drugs, Hans Schaefer, Thomas E. Redelmeier, Gerhard J. Nohynek, and Jurgen Lademann
216. Topical Cortocosteroids, Francisco A. Kerdel and Isabel Valencia
217. Topical Retinoids, Anna L. Chien, John J. Voorhees, and Sewon King
218. Topical Antibiotics, Mark Bonner and William James
219. Topical Antifungal Agents, Whitney High and James E. Fitzpatrick
220. Topical and Intralesional Cytotoxic Agents, Aieska De Souza, Megan M. Moore, and Bruce E. Strober
221. Topical Immunomodulators, Edward M. Esparza and Robert Sidbury
222. Other Topical Medications, Kenneth Katz
223. Photoprotection, Henry W. Lim
Section 37: Systemic Therapy
224. Systemic Glucocorticoids, Victoria P. Werth
225. Dapsone, Joni G. Sago and Russell P. Hall III
226. Aminoquinolines, Susannah E. McClain, Jeffrey R. LaDuca, and Anthony A. Gaspari
227. Cytotoxic and Antimetabolic Agents, Whitney A. High and James Fitzpatrick
228. Retinoids, Anders Vahlquist and Jean-Hilaire Saurat
229. Antihistamines, Robert A. Wood
230. Antibiotics, Christopher C. Gasbarre, Steven K. Schmitt, and Kenneth J. Tomecki
231. Antiviral Drugs, Dirk M. Elston
232. Oral Antifungal Agents, Reza Jacob and Nellie Konnikov
233. Mycophenolate Mofetil, Cyclosporine, and Related Immunosuppressive Therapies, Jeffrey P. Callen
234. Immunobiologicals, Cytokines, and Growth Factors in Dermatology, Stephan K. Richardson and Joel M. Gelfand
235. Anti-angiogenic Agents, Ricardo L. Berrios, Michael Y. Bonner, Jonathan Hofmekler, and Jack L. Arbiser
236. Drug Interactions, Steven E. Wolverton
Section 38: Physical Treatments
237. Phototherapy, Craig A. Elmets, Brian Pollack, and Jennifer Cafardi
238. Photochemotherapy and Photodynamic Therapy, Herbert Hoenigsmann, Rolf-Markus Szeimies, and Robert Knobler
239. Lasers and Flash Lamps in Dermatology, Michael Landthaler, Wolfgang Baeumler, and Ulrich Hohenleutner
240. Radiotherapy, Lynn Wilson and Roy Decker
Section 39: Complementary and Alternative Dermatology
241. Complementary and Alternative Medicine in Dermatology, Alan Dattner
Section 40: Surgery in Dermatology
242. Dermatologic Surgery: Introduction to Anatomy and Approach, Sumaira Aasi
243. Excisional Surgery and Repair, Flaps, and Grafts, Jessica M. Sheehan, Melanie Kingsley, and Thomas E. Rohrer
244. Mohs Micrographic Surgery, Joseph Alcalay and Ronen Alkalay
245. Nail Surgery, Robert Baran
246. Cryosurgery and Electrosurgery, Justin Vujevich and Leonard Goldberg
247. Surgical Complications, Richard Bennett
248. Wound Repair: Mechanisms and Practical Considerations, Vincent Falanga and Satori Iwamoto
249. Treatment for Varicose and Telangiectatic Leg Veins, Robert A. Weiss and Margaret Weiss
Section 41: Cosmetic Dermatology
250. Cosmetics and Skin Care in Dermatology, Leslie Baumann
251. Skin Resurfacing: Ablative Lasers, Chemical Peels, and Dermabrasion, Elizabeth Tanzi and Tina Alster
252. Cosmetic Applications of Non-Ablative Lasers and Other Light Devices, Elliott T. Weiss, Anne M. Chapas, and Roy G. Geronemus
253. Liposuction Using Tumescent Local Anesthesia, William Stebbins, Aimee Leonard, and C. William Hanke
254. Soft Tissue Augmentation, Lisa M. Donofrio
255. Botulinum Toxin, Richard G. Glogau
256. Hair Transplantation and Alopecia Reduction, Walter P. Unger, Robin H. Unger, and
Fitzpatrick’s Dermatology in General Medicine 8th Edition PDF Ebook
Preface
Acknowledgments
PART I: INTRODUCTION
Section 1: General Considerations
1. The Epidemiology and Burden of Skin Disease, Martin A. Weinstock and Mary-Margaret Chren
2. Evidence-Based Dermatology, Michael Bigby, Rosamaria Corona, and Moyses Szklo
3. Global Health in Dermatology, Roderick Hay
4. Public Health in Dermatology, Hywell C. Williams, Sinead Langan, and Carsten Flohr
Section 2: Approach to Dermatologic Diagnosis
5. Structure of Skin Lesions and Fundamentals of Clinical Diagnosis, Amit Garg, Nikki A. Levin, and Jeffrey D. Bernhard
6. Basic Pathologic Reactions of the Skin, Klaus Wolff
Section 3: Overview of Biology, Development, and Structure of Skin
7. Development and Structure of Skin, David H. Chu
8. Genetics in Relation to the Skin, John McGrath and Irwin McLean
9. Racial Considerations: Skin of Color, Kavitha K. Reddy, Yolanda M. Lenzy, Katherine L. Brown, and Barbara A. Gilchrest
PART II: DISORDERS PRESENTING IN SKIN AND MUCOUS MEMBRANES
Section 4: Inflammatory Disorders Based on T-Cell Reactivity and Dysregulation
10. Innate and Adaptive Immunity for the Skin, Georg Stingl and Robert L. Modlin
11. Cytokines, Thomas Kupper and Ifor Williams
12. Chemokines, Anke S. Lonsdorf and Sam T. Hwang
13. Allergic Contact Dermatitis, Kathryn A. Zug and Mari Paz Castanedo
14. Atopic Dermatitis (Atopic Eczema), Donald Leung, Lawrence F. Eichenfield, and Mark Boguniewicz
15. Nummular Eczema and Lichen Simplex Chronicus/Prurigo Nodularis, Susan Burgin
16. Vesicular Palmoplantar Eczema, Daven N. Doshi, Carol E. Cheng, and Alexa B. Kimball
17. Autosensitization Dermatitis, Don Belsito
18. Psoriasis, James T. Elder
19. Psoriatic Arthritis, Dafna D. Gladman and Vinod Chandran
20. Reactive Arthritis, John D. Carter
21. Pustular Eruptions of Palms and Soles, Ulrich Mrowietz
22. Seborrheic Dermatitis, Chad M. Hivnor and Chris D. Collins
23. Exfoliative Dermatitis, Jane Margaret Grant-Kels, Flavia Fedeles, and Marti J. Rothe
24. Pityriasis Rubra Pilaris, Daniela Bruch-Gerharz and Thomas Ruzicka
25. Parapsoriasis and Pityriasis Lichenoides, Gary S. Wood, Chung-Hong Hu, and Rosemarie Liu
26. Lichen Planus, Mark R. Pittelkow and Mazen Daoud
27. Lichen Nitidus, Mark R. Pittelkow and Mazen Daoud
28. Graft-versus-Host Disease, Ed Cowen
29. Skin Disease in Acute and Chronic Immunosuppression, Benjamin D. Ehst and Andrew Blauvelt
Section 5: Inflammatory Diseases Based on Neutrophilsand Eosinophils
30. Regulation of the Production and Activation of Neutrophils, Steven M. Holland
31. Regulation of the Production and Activation of Eosinophils, Kristin M. Leiferman
32. Acute Febrile Neutrophilic Dermatosis (Sweet Syndrome), Philip R. Cohen, Herbert Hoenigsmann, and Razelle Kurzrock
33. Pyoderma Gangrenosum, Frank C. Powell, Bridget C. Hackett, and Daniel Wallach
34. Granuloma Faciale, David A. Mehregan and Darius R. Mehregan
35. Sub-Corneal Pustular Dermatosis (Sneddon-Wilkinson Disease), Franz Trautinger and Herbert Hoenigsmann
36. Eosinophils in Cutaneous Diseases, Kristin M. Leiferman and Margot S. Peters
Section 6: Inflammatory Diseases Based on Abnormal Humoral Reactivity and Other Inflammatory Diseases
37. Humoral Immunity and Complement, Lela Lee
38. Urticaria and Angioedema, Allen Kaplan
39. Erythema Multiforme, Jean C. Roujeau
40. Epidermal Necrolysis (Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis), L. Valeyrie-Allanore and Jean C. Roujeau
41. Cutaneous Reactions to Drugs, Neil H. Shear and Sandra R. Knowles
42. Pityriasis Rosea, Andrew Blauvelt
43. Erythema Annulare Centrifugum and Other Figurate Erythemas, Walter H. C. Burgdorf
44. Granuloma Annulare, Julie S. Prendiville
Section 7: Disorders of Epidermal Differentiation and Keratinization
45. Epidermal Stem Cells, Rebecca Morris
46. Epidermal Growth and Differentiation, Tung-Tien Sun
47. Skin as an Organ of Protection, Ehrhardt Proksch and Jens-Michael Jensen
48. Irritant Contact Dermatitis, Antoine Amado, Apra Sood, and James S. Taylor
49. The Ichthyoses, Philip Fleckman and John DiGiovanna
50. Inherited Keratodermas of Palms and Soles, Mozheh Zamiri, Maurice A.M. van Steensel, and Colin S. Munro
51. Acantholytic Disorders of the Skin, Susan Burge and Alain Hovnanian
52. Porokeratosis, Alan D. Irvine and Grainne O’Regan
Section 8: Disorders of Epidermal and Dermal-Epidermal Cohesion and Vesicular and Bullous Disorders
53. Epidermal and Epidermal-Dermal Abrasion, Leena Bruckner-Tuderman and Aimee S. Payne
54. Pemphigus, John R. Stanley and Aimee S. Payne
55. Paraneoplastic Pemphigus, Grant Anhalt and Daniel Mimouni
56. Bullous Pemphigoid, Donna A. Culton, Zhi Liu, and Luis A. Diaz
57. Cicatricial Pemphigoid, Kim B. Yancey
58. Linear Immunoglobulin A Dermatosis and Chronic Bullous Disease of Childhood, Caroline L. Rao and Russell P. Hall, III
59. Pemphigoid Gestationis (Herpes Gestationis), Jeff Shornick
60. Epidermolysis Bullosa Acquisita, David T. Woodley and Mei Chen
61. Dermatitis Herpetiformis, Arash Ronaghy, Stephen I. Katz, and Russell P. Hall, III
62. Inherited Epidermolysis Bullosa, M. Peter Marinkovich
Section 9: Disorders of the Dermal Connective Tissue
63. Collagens, Elastic Fibers, and Other Extracellular Matrix Proteins of the Dermis, Thomas Krieg, Monique Aumailley, Manual Koch, Mon-Li Chu, and Jouni Uitto
64. Morphea, Stephanie Saxton-Daniels and Heidi Jacobe
65. Lichen Sclerosus, Ulrich Hengge
66. Dermal Hypertrophies and Benign Fibroblastic/Myofibroblastic Tumors, Christine Ko
67. Anetoderma and Other Atrophic Disorders of the Skin, Julie Powell and Catherine Maari
68. Ainhum and Pseudoainhum, Robert T. Brodell and Stephen E. Helms
69. Acquired Perforating Disorders, Bethanee Schlosser and Julia Minocha
Section 10: Disorders of Subcutaneous Tissue
70. Panniculitis, Iris K. Aronson, Patricia M. Fishman, and Sophie M. Worobec
71. Lipodystrophy, Abhimanyu Garg
Section 11: Disorders of Melanocytes
72. Biology of Melanocytes, Hee-Young Park, Marita G. Kosmadaki, Marinya Pongpudpunth, Jin Lee, and Mina Yaar
73. Albinism and Other Genetic Disorders of Pigmentation, Thomas J. Hornyak
74. Vitiligo, Stanca A. Birlea, Richard A. Spritz, and David A. Norris
75. Hypomelanoses and Hypermelanoses, Hilde Lapeere, Barbara Boone, Sofie De Schepper, Evelien Verhaeghe, Mireille Van Gele, Katia Ongenae, Nanja Van Geel, Jo Lambert, Lieve Brochez, and Jean-Marie Naeyaert
Section 12: Disorders of the Oral and Genital Integument
76. Biology and Pathology of the Oral Cavity, Sook-Bin Woo
77. Diseases and Disorders of the Male Genitalia, Christopher Barry Bunker
78. Diseases and Disorders of the Female Genitalia, Lynne Margesson and F. William Danby
PART III: DISORDERS OF THE SKIN APPENDAGES
Section 13: Disorders of the Sebaceous Glands
79. Biology of Sebaceous Glands, Amanda M. Nelson and Diane M. Thiboutot
80. Acne Vulgaris and Acneiform Eruptions, Andrea L. Zaenglein, Emmy M. Graber, Diane M. Thiboutot, and John S. Strauss
81. Rosacea, Michelle Terez Pelle
82. Perioral Dermatitis, Leslie P. Lawley and Sareeta R.S. Parker
Section 14: Disorders of the Eccrine and Apocrine Glands
83. Biology of Eccrine, Apocrine, and Apoeccrine Sweat Glands, Theodora Marie Mauro
84. Disorders of the Eccrine Sweat Glands and Sweating, Robert D. Fealey and Adelaide A. Herbert
85. Disorders of the Apocrine Sweat Glands, Christos C. Zouboulis and Fragkiski Tsatsou
Section 15: Disorders of the Hair and Nails
86. Biology of Hair Follicles, George Cotsarelis and Vladimir Botchkarev
87. Keratosis Pilaris and Other Inflammatory Follicular Keratotic Syndromes, Paradi Mirmirani and Maureen Rogers
88. Hair Growth Disorders, Nina Otberg and Jerry Shapiro
89. Biology of Nails and Nail Disorders, Antonella Tosti and Bianca Maria Piraccini
PART IV: DISORDERS DUE TO THE ENVIRONMENT
Section 16: Disorders Due to Ultraviolet Radiation
90. Fundamentals of Cutaneous Photobiology and Photoimmunology, Irene Kochevar, Charles Taylor, and Jean Krutmann
91. Abnormal Responses to Ultraviolet Radiation: Idiopathic, Probably Immunologic, and Photoexacerbated, Paul Bergstresser
92. Abnormal Responses to Ultraviolet Radiation: Photosensitivity Induced by Exogenous Agents, Henry W. Lim
Section 17: Skin Changes Due to Other Physical and Chemical Factors
93. Thermoregulation, Dean L. Kellogg, Jr.
94. Cold Injuries, Gerald E. Pieard, Pascale Quatresooz, and Claudine Pierard-Franchimont
95. Thermal Injuries, Robert L. Sheridan
96. Skin Problems in Amputees, Calum Lyon and Michael H. Beck
97. Skin Problems in Ostomates, Calum Lyon and Michael Beck
98. Corns and Calluses, Thomas M. DeLauro and Nicole M. DeLauro
99. Sports Dermatology, Dirk M. Elston
100. Decubitus (Pressure) Ulcers, Jennifer Gloeckner Powers, Lilian M. Odo, and Tania J. Phillips
101. Body Art, Anne Laumann
PART V: NEUROCUTANEOUS AND
PSYCHOCUTANEOUS ASPECTS OF SKIN DISEASE
Section 18: Neurocutaneous and Psychocutaneous Skin Disease
102. Neurobiology of the Skin, Thomas Luger and Martin Steinhoff
103. Pathophysiology and Clinical Aspects of Pruritus, Gil Yosipovitch and Tejesh S. Patel
104. Psychocutaneous Skin Disease, Evan Rieder and Francisco A. Tausk
105. Cutaneous Manifestations of Drug Abuse, Richard A. Johnson and Haley Naik
106. Skin Signs of Physical Abuse, Howard Pride
PART VI: SKIN CHANGES ACROSS THE LIFE SPAN
Section 19: From Birth to Old Age
107. Neonatal, Pediatric, and Adolescent Dermatology, Mary W. Chang
108. Skin Changes and Diseases in Pregnancy, Julie K. Karen and Miriam Keltz Pomeranz
109. Aging of Skin, Barbara Ann Gilchrest and Mina Yaar
PART VII: NEOPLASIA
Section 20: Carcinogenesis
110. Genome Instability, DNA Repair, and Cancer, Kenneth H. Kraemer and Thomas M. Ruenger
111. Chemical Carcinogenesis, Andrzej A. Dlugosz
112. Ultraviolet Radiation Carcinogenesis, Masaoki Kawasumi and Paul Nghiem
Section 21: Epidermal and Appendageal Tumors
113. Epithelial Precancerous Lesions, Karyanne O. Duncan, John K. Geisse, and David J. Leffell
114. Squamous Cell Carcinoma, David J. Leffell and Douglas Grossman
115. Basal Cell Carcinoma, David J. Leffell and John Carucci
116. Basal Cell Nevus Syndrome, Anthony E. Oro and Jean Y. Tang
117. Keratoacanthoma, Lorenzo Cerroni and Helmut Kerl
118. Benign Epithelial Tumors, Hamartomas, and Hyperplasias, Neil Swanson
119. Appendage Tumors and Hamartomas of the Skin, Divya Srivastava and R. Stan Taylor
120. Merkel Cell Carcinoma, Andrew Tegeder, Olga Afanasiev, and Paul Nghiem
121. Mammary and Extramammary Paget Disease, Sherrif F. Ibrahim, Roy C. Greken, and Isaac M. Neuhaus
Section 22: Melanocytic Tumors
122. Benign Neoplasias and Hyperplasias of Melanocytes, James M. Grichnik, Arthur R. Rhodes, and Arthur J. Sober
123. Atypical (Dysplastic) Melanocytic Nevi, James Grichnik and Margaret A. Tucker
124. Cutaneous Melanoma, Evans C. Bailey, Arthur J. Sober, Hensin Tsao, Martin C. Mihm, Jr., and Timothy M. Johnson
Section 23: Tumors and Hyperplasias of the Dermis and Subcutaneous Fat
125. Malignant Fibrous, Fibrohistiocytic, and Histiocytic Tumors of the Dermis, Juergen C. Becker and Selma Ugurel
126. Vascular Tumors, Ilona J. Frieden and Erin Mathes
127. Neoplasias and Hyperplasias of Muscular and Neural Origin, Lucile E. White, Ross M. Levy, and Murad Alam
128. Kaposi Sarcoma, Erwin Tschachler
129. Neoplasms of Subcutaneous Fat, Thomas Brenn
PART VIII: THE SKIN IN SYSTEMIC DISEASE
Section 24: Skin in Nutritional, Metabolic, and Heritable Disease
130. Cutaneous Features of Nutritional Disease, Albert C. Yan and Melinda Jen
131. Cutaneous Changes in Errors of Amino Acid Metabolism, Peter Itin
132. The Porphyrias, David R. Bickers and Jorge Frank
133. Amyloidosis and the Skin, Helen J. Lachmann and Philip Hawkins
134. The Systemic Monogenic Autoinflammatory Diseases, Raphaela Goldbach-Mansky
135. Xanthomatoses and Lipoprotein Disorders, Ernst Schaefer and Raul Santos
136. Fabry Disease, Atul Mehta and Catherine H. Orteu
137. Lipoid Proteinosis and Heritable Disorders of Connective Tissue, Jon Dyer
138. Cutaneous Mineralization and Ossification, Janet Fairley
139. Hereditary Disorders of Genome Instability and DNA Repair, Thomas Ruenger, Kenneth H. Kraemer, and John DiGiovanna
140. Tuberous Sclerosis Complex, Thomas N. Darling
141. The Neurofibromatoses, Robert H. Listernick and Joel Charrow
142. Ectodermal Dysplasias, Nnenna Agim, Alanna F. Bree, and Virginia P. Sybert
143. Genetic Immunodeficiency Diseases, Ramsey Fuleihan and Amy Paller
Section 25: Skin Manifestations of Bone Marrow or Blood Chemistry Disorders
144. Hematologic Diseases, Warren Piette
145. Cutaneous Lymphoma, Marc Beyer and Wolfgang Sterry
146. Inflammatory Diseases That Simulate Lymphomas: Cutaneous Pseudolymphomas, Gary S. Wood
147. Cutaneous Langerhans Cell Histiocytosis, Carlo Gelmetti
148. Non-Langerhans Cell Histiocytosis, Carlo Gelmetti
149. Mastocytosis, Michael D. Thorp
Section 26: Skin Manifestations of Internal Organ Disorders
150. The Skin and Disorders of the Alimentary Trace, the Hepatobiliary System, Kidney and Cardiopulmonary System, Graham A. Johnston and Robin A.C. Graham-Brown
151. Diabetes Mellitus and Other Endocrine Diseases, Andrea A. Kalus, Andy J. Chien, and John E. Olerud
152. Sarcoidosis, Richard M. Marchell, Bruce Thiers, and Marc Judson
153. Cutaneous Manifestations of Internal Malignant Disease, Christine DeWitt, Lucinda Buescher, and Stephen P. Stone
Section 27: The Skin in Vascular and Connective Tissue and Other Autoimmune Disorders
154. Mechanisms of Autoimmune Disease, Joseph Craft and Insoo Kang
155. Lupus Erythematosus, Richard D. Sontheimer and Melissa I. Costner
156. Dermatomyositis, Richard D. Sontheimer and Melissa I. Costner
157. Scleroderma (Systematic Sclerosis), P. Moinzadeh, C.P. Denton, T. Kriegm and C.M. Black
158. Scleredema and Scleromyxedema, Roger H. Weenig and Mark R. Pittelkow
159. Relapsing Polychondritis, Camille Frances
160. Rheumatoid Arthritis, Rheumatic Fever, and Gout, Warren Piette
161. Sjoegren Syndrome, Gabor Illei
Section 28: The Skin in Inflammatory and Other Vascular Disorders
162. Endothelium in Inflammation and Angiogenesis, Peter Petzelbauer, Robert Loewe, and Jordan S. Pober
163. Cutaneous Necrotizing Venulitis, Nicholas A. Soter
164. Systemic Necrotizing Arteritis, Peter Merkel
165. Erythema Elevatum Diutinum, Nneka J. Comfere and Lawrence E. Gibson
166. Adamantiades-Behcet Disease, Christos C. Zouboulis
167. Kawasaki Disease, Anne H. Rowley
168. Pigmented Purpuric Dermatoses, Theresa Devere
169. Cryoglobulinemia and Cryofibrinogenemia, Holger Schmidt and Gerald Braun
170. Raynaud Phenomenon, John H. Klippel
171. Malignant Atrophic Papulosis (Degos Disease), Dan Lipsker
172. Vascular Malformations, Laurence M. Boon
173. Cutaneous Changes in Peripheral Vascular Arterial Disease, Veerendra Chadachan, Steven M. Dean, and Robert T. Eberhardt
174. Cutaneous Changes in Venous and Lymphatic Insufficiency, Craig N. Burkhart, Chris Adigun, and Claude S. Burton
PART IX: DISEASE DUE TO MICROBIAL AGENTS, INFESTATIONS, BITES, AND STINGS
Section 29: Bacterial Disease
175. General Considerations of Bacterial Diseases, Noah Craft
176. Superficial Cutaneous Infections and Pyodermas, Noah Craft
177. Gram-Positive Infections Associated with Toxin Production, Jeffrey B. Travers and Nick Mousdicas
178. Non-Necrotizing Infections of the Dermis and Subcutaneous Fat: Cellulitis and Erysipelas, Adam D. Lipworth, Arturo Saavedra, Arnold N. Weinberg, and Richard Allen Johnson
179. Necrotizing Soft Tissue Infections: Necrotizing Fasciitis, Gangrenous Cellulitis, and Myonecrosis, Adam P. Lipworth, Arturo Saavedra, Arnold N. Weinberg, and Richard Allen Johnson
180. Gram-Negative Coccal and Bacillary Infections, Myron Cohen and David Weber
181. The Skin in Infective Endocarditis, Sepsis, Septic Shock, and Disseminated Intravascular Coagulation, Laura Korb Ferris and Joseph C. English
182. Bartonellosis, Timothy Berger and Francisco G. Bravo
183. Miscellaneous Bacterial Infections with Cutaneous Manifestations, Scott A. Norton
184. Tuberculosis and Infections with Atypical Mycobacteria, Aisha Sethi and Bernard Naafs
185. Actinomyosis, Nocardiosis, and Actinomycetoma, Francisco G. Bravo, Roberto Arenas, and Daniel Asz Sigall
186. Leprosy, Delphine Lee, Thomas H. Rea, and Robert L. Modlin
187. Lyme Borreliosis, Meera Mahalingam, Jag Bhawan, Daniel B. Eisen, and Linden Hu
Section 30: Fungal Diseases
188. Superficial Fungal Infection, Amit Garg and Stefan Schieke
189. Yeast Infections: Candidiasis, Tinea (Pityriasis) Versicolor and Malassezia (Pityrosporum) Folliculitis, Roopal Vashi Kundu and Amit Garg
190. Deep Fungal Infections, Roderick J. Hay
Section 31: Viral and Rickettsial Diseases
191. Viral Diseases: General Considerations, L. Katie Morrison, Ammar Ahmed, Vandana Madkan, Natalia Mendoza, and Stephen Tyring
192. Exanthematous Viral Diseases, Leah T. Belazarian, Mayra E. Lorenzo, Andrea L. Pearson, Susan M. Sweeney, and Karen Wiss
193. Herpes Simplex, Adriana R. Marques and Jeffrey I. Cohen
194. Varicella and Herpes Zoster, Kenneth Schmader and Michael N. Oxman
195. Poxvirus Infections, Caroline Piggott, Sheila Fallon Friedlander, and Wynnis Tom
196. Warts, Elliott J. Androphy and Reinhard Kirnbauer
197. Human Retroviral Disease: Human T-Lymphotropic Viruses, Erwin Tschachler
198. Cutaneous Manifestations of Human Immunodeficiency Virus, Lily Changchien Uihlein, Arturo Saavedra, and Richard Allen Johnson
199. The Rickettsioses, Ehrlichioses, and Anaplasmoses, Warren Heyman, Sandra Kopp, and Justin Green
Section 32: Sexually Transmitted Diseases
200. Syphilis, Ken Katz
201. Endemic (Non-venereal) Treponematoses, Samer
Ghosn and Nadine Marrouch
202. Chancroid, Stephan Lautenschlager
203. Lymphogranuloma Venereum, Rim Ishak and Samer Ghosn
204. Granuloma Inguinale, Abdul-Ghani Kibbi, Ruba F. Bahhady, and Myrna El-Shareef
205. Gonorrhea and Other Mucosal-Based Venereal Diseases, Ted Rosen
Section 33: Infestations, Bites, and Stings
206. Leishmaniasis and Other Protozoan Infections, Joelle Malek and Samar Ghosn
207. Helminthic Infections, Jay Keystone and Kathy Suh
208. Scabies, Other Mites, and Pediculosis, Craig N. Burkhart and Craig G. Burkhart
209. Bites and Stings of Terrestrial and Aquatic Life, Jennifer Daly and Mark Jordan Scharf
210. Arthropod Bites and Stings, Robert A. Schwartz and Christopher J. Steen
PART X: OCCUPATIONAL SKIN DISEASES AND SKIN DISEASES DUE TO BIOLOGIC WARFARE
Section 34: Occupational Skin Diseases
211. Occupational Skin Disease due to Irritants and Allergens, James S. Taylor and Apra Sood
212. Occupational Noneczematous Skin Diseases Due to Biologic, Physical, and Chemical Agents: Introduction, James S. Taylor and Apra Sood
Section 35: The Skin in Bioterrorism and Biologic Warfare
213. Cutaneous Manifestations of Biologic, Chemical, and Radiologic Terrorism Attacks, Scott A. Norton
PART XI: THERAPEUTICS
Section 36: Topical Therapy
214. Principles of Topical Therapy, Aieska de Souza and Bruce E. Strober
215. Pharmacokinetics and Topical Applications of Drugs, Hans Schaefer, Thomas E. Redelmeier, Gerhard J. Nohynek, and Jurgen Lademann
216. Topical Cortocosteroids, Francisco A. Kerdel and Isabel Valencia
217. Topical Retinoids, Anna L. Chien, John J. Voorhees, and Sewon King
218. Topical Antibiotics, Mark Bonner and William James
219. Topical Antifungal Agents, Whitney High and James E. Fitzpatrick
220. Topical and Intralesional Cytotoxic Agents, Aieska De Souza, Megan M. Moore, and Bruce E. Strober
221. Topical Immunomodulators, Edward M. Esparza and Robert Sidbury
222. Other Topical Medications, Kenneth Katz
223. Photoprotection, Henry W. Lim
Section 37: Systemic Therapy
224. Systemic Glucocorticoids, Victoria P. Werth
225. Dapsone, Joni G. Sago and Russell P. Hall III
226. Aminoquinolines, Susannah E. McClain, Jeffrey R. LaDuca, and Anthony A. Gaspari
227. Cytotoxic and Antimetabolic Agents, Whitney A. High and James Fitzpatrick
228. Retinoids, Anders Vahlquist and Jean-Hilaire Saurat
229. Antihistamines, Robert A. Wood
230. Antibiotics, Christopher C. Gasbarre, Steven K. Schmitt, and Kenneth J. Tomecki
231. Antiviral Drugs, Dirk M. Elston
232. Oral Antifungal Agents, Reza Jacob and Nellie Konnikov
233. Mycophenolate Mofetil, Cyclosporine, and Related Immunosuppressive Therapies, Jeffrey P. Callen
234. Immunobiologicals, Cytokines, and Growth Factors in Dermatology, Stephan K. Richardson and Joel M. Gelfand
235. Anti-angiogenic Agents, Ricardo L. Berrios, Michael Y. Bonner, Jonathan Hofmekler, and Jack L. Arbiser
236. Drug Interactions, Steven E. Wolverton
Section 38: Physical Treatments
237. Phototherapy, Craig A. Elmets, Brian Pollack, and Jennifer Cafardi
238. Photochemotherapy and Photodynamic Therapy, Herbert Hoenigsmann, Rolf-Markus Szeimies, and Robert Knobler
239. Lasers and Flash Lamps in Dermatology, Michael Landthaler, Wolfgang Baeumler, and Ulrich Hohenleutner
240. Radiotherapy, Lynn Wilson and Roy Decker
Section 39: Complementary and Alternative Dermatology
241. Complementary and Alternative Medicine in Dermatology, Alan Dattner
Section 40: Surgery in Dermatology
242. Dermatologic Surgery: Introduction to Anatomy and Approach, Sumaira Aasi
243. Excisional Surgery and Repair, Flaps, and Grafts, Jessica M. Sheehan, Melanie Kingsley, and Thomas E. Rohrer
244. Mohs Micrographic Surgery, Joseph Alcalay and Ronen Alkalay
245. Nail Surgery, Robert Baran
246. Cryosurgery and Electrosurgery, Justin Vujevich and Leonard Goldberg
247. Surgical Complications, Richard Bennett
248. Wound Repair: Mechanisms and Practical Considerations, Vincent Falanga and Satori Iwamoto
249. Treatment for Varicose and Telangiectatic Leg Veins, Robert A. Weiss and Margaret Weiss
Section 41: Cosmetic Dermatology
250. Cosmetics and Skin Care in Dermatology, Leslie Baumann
251. Skin Resurfacing: Ablative Lasers, Chemical Peels, and Dermabrasion, Elizabeth Tanzi and Tina Alster
252. Cosmetic Applications of Non-Ablative Lasers and Other Light Devices, Elliott T. Weiss, Anne M. Chapas, and Roy G. Geronemus
253. Liposuction Using Tumescent Local Anesthesia, William Stebbins, Aimee Leonard, and C. William Hanke
254. Soft Tissue Augmentation, Lisa M. Donofrio
255. Botulinum Toxin, Richard G. Glogau
256. Hair Transplantation and Alopecia Reduction, Walter P. Unger, Robin H. Unger, and
Fitzpatrick’s Dermatology in General Medicine 8th Edition PDF Ebook
About the Authors
Professor of Dermatology, University of North Carolina, Chapel Hill, NC
Dean Emeritus, University of Rochester School of Medicine and Dentistry, Rochester, NY
Dean Emeritus, University of Rochester School of Medicine and Dentistry, Rochester, NY
Director, National Institute of Arthritis and
Musculoskeletal and Skin Diseases
National Institutes of Health
Bethesda, Maryland
Professor and Chair of Dermatology, Department of Dermatology, BostonUniversity School of Medicine, Boston, Massachusetts
Walter J. Hamlin Professor and Chair of Dermatology, Professor of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
Professor of Dermatology and Surgery, Chief, Section of Dermatologic Surgery and Cutaneous Oncology, Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut
Professor and Chairman Emeritus, Department of Dermatology, The University of Vienna Medical School, Vienna General Hospital, Vienna, Austria.
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